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1. User guide
Dont go to close the enemys, Twisted Fate die easyli.
At start play def, and use Wild Cards to kill minions and hurt champions.
Then you are out of mana, look at gate, if its ready, go back and up again.
Learn to hit gold card almost everytime, very importent!
AP runes and/or health runes.
Twisted Fate do not have a lot of health, so its good with 50-100 more max health from runes, so he can survive at start.
AP, health, mana and mana regen, if you have no health runes, its a good idea to get some health from Masteries.