What are the universally useful runes that most people run these days?
The ones I know of:
Quints: Movement Speed, Gp per 10
Marks: Armor Penetration, Magic Penetration
Seals: Flat Armor, Gp per 10, Scaling Health
Glyphs: Scaling Magic Resist, Flat Magic Resist
Anything I'm missing?
AP Quints are popular, AD Reds and Quints are essential for starting out ADCs, Lifesteal Quints are nice for some junglers.
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