Concerning Ashe, which mastery is better than the other?
3 points Good Hands vs. 3 points Perseverence
2 points Alacrity vs. 2 points Offensive Mastery
If it makes a difference, here's my build: Berserker's Greaves, Infinity Edge, Phantom Dancer, Black Cleaver, Bloodthirster, Banshee's Veil.
Also, I think most of us would agree that 21/0/9 is the way to go. If not, feel free to refute.
21/0/9 or 9/0/21 are both good.
The 21 offense is self explanatory, more damage and higher crit damage.
The 21 utility may not be so obvious but when you consider the mana regen, move speed and Ghost/Flash cooldowns (duration) it is very well worth your while.
Personally I can never make up my mind which to choose. The marginal damage advantage early game or be the flash queen. As Ashe you can not live without Ghost/Flash since you are squishy as hell.
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