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Sounds like her config file is broken.
harddrive/program files/league of legends/config/
inside is a file called 'game.cfg'
Run the launcher.
Launce the game.
Play a custom game with just you.
Set your screen resolution and settings to what you prefer.
The game should remember it now.
Try this, your DX looks fine, nothing that would be causing this issue stands out. More than likely there is a problem with the game.cfg file and it needs to be redone.