Couldn't close the screen, couldn't change runes, summoner spells, or masteries.
Here is a screen shot:
Later this same game I got a leaver (I think my only one in 1000+ games) because I wouldn't stay connected in the game after about 10 minutes of being fine to start.
© 2014 Riot Games, Inc. All rights reserved. Riot Games, League of Legends and PvP.net are trademarks, services marks, or registered trademarks of Riot Games, Inc.