-If I don't build any Armor Pen items...and don't have armor pen runes...does it make this mastery useless?
Sam Is Whoa
Early game yes it does but early i mean early like lvl 1-3 and only against squishy carries without armor runes.
So short answer its not advantageous without runes or items. Your masteries should compliment your runes.
It is never useless if you're playing an AD character.
Hes asking about weapon mastery. That one is useless without the second armor pen mastery.
Your better off going ad per level and lifesteal mastery if you dont have armor pen runes. It is only 1 mastery point though but that 1 point could be used for advanced flash or heal.
Short answer again is its useless. You wont notice a difference.
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