Personally I have found a lot of success with this setup:
7 flat ad reds
2 m pen reds
9 scaling hp yellows
9 flat ap blues
1 ap quint
1 move speed quint
1 flat hp quint.
At level 3 you can proc both passives, but I carry ignite with the mastery point so if I go for the kill pre-3 I can have both passives proc'd.
NO-ONE expects to see akali with that many hp bars and my stats in ranked with her are 15-7-12 per game average.
 PS: I run standard 21-9-0 masteries getting the 3 points in ad then all ap for offense, then getting the hp bonuses in the defensive tree
I'm trying to squeeze in 3x MS Quints while still procing both passives. I want to start Boots 3x pots.
8x Flat AD
9x Flat AP
1x Flat AP
So far I don't think I'm able to go 3x MS Quints while still procing both passives, but I'd love to find out if anyone has.
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