AD Ezreal > Karthus
Ezreal can shoot outside of defile range, an Ezreal can teleport OVER walls of pain, and lay waste...are you joking?
Karthus deals more damage, but Ezreal has sheer range to his advantage. Technically, Ezreal doesn't have to get close enough to get hit by q spam, but will get crushed if he gets too close.
And a good Karthus can read how Ezreal uses his Mystic Shot and jukes him.
It goes both ways.
Nihil Sine Nefas
No matter how good you are with LW, they really aren't that hard to dodge even with just boots1.
Depends on how they build ezreal mang..
Karthus with Zhonyas and 5 Archangels.
An enemy has been slain.
Karthus, he'll make it draw at least.
Only so much you can attempt to flash dodge before lay waste catches you, it's much easier to dodge ez's Q than karthus's LW.
Havent seen a Ez dodge my Q spam long enough to kill me 1v1 So yeah, maybe a really good ez with more games of experiece will be able to but till i meet him.
You get to have a feel for his Q's after awhile, its rather hard at first but then it'll come to you naturally like yi with right click
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