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Mundo says: What mana? Mundo SMASH!
Sivir says: Any summoner who uses mana runes chooses wisely.
Tristian says : BOOM! (With her it sorta depends, do you run OOM fast? Then they are not to bad. Otherwise get something else)
Basicly it depends on how much mana you go through on that hero. Running OOM? Good investment. Doing fine without? Get something else.